Possible interaction between visfatin, periodontal infection, and other systemic diseases: A brief review of literature
نویسندگان
چکیده
Gingivitis and periodontitis are common bacterial infections caused by a variety of microorganisms. Despite the microorganisms' roles as etiologic agents, inflammation-induced substances also have crucial parts in the loss of connective tissue and the supporting alveolar bone. Visfatin is a pleiotropic mediator, which acts as growth factor, cytokine, and pre-B-cell colony-enhancing factor. A positive correlation was detected between the serum/plasma levels of visfatin and inflammatory disorders such as diabetes mellitus and cardiovascular disease. In addition, the visfatin level was higher in saliva and the gingival crevicular fluid (GCF) of subjects with periodontal disease. This review defined current, predictable patterns of possible interaction of visfatin with periodontal infection and other systemic diseases, using PubMed and Medline databases searching for articles written in English. Peer-reviewed articles were targeted using the following keywords: "visfatin," "periodontal disease," "inflammatory mediator," and "biomarker." Available full-text articles were read, and related articles were also scrutinized, while a hand search was also performed. Search was confined to human studies, and articles written in English and published between 1985 and 2016 were selected. It was concluded that periodontal infection and other systemic diseases could be related to the levels of visfatin in GCF, saliva, and serum as a biomarker of these diseases.
منابع مشابه
Is there any Association Between Human Lymphotropic Virus Type I (HTLV-I) Infection and Systemic Lupus Erythematosus? An Original Research and Literature Review
متن کامل
Comparing Gingival Crevicular Fluid Visfatin Levels Between Patients with Endometrial Cancer and Chronic Periodontitis and Healthy Controls
Background and purpose: The association between periodontal diseases and endometrial cancer (EC) has been assessed in some studies but the probable role of inflammatory factors such as visfatin is unknown. This study aimed at evaluating the levels of visfatin in gingival crevicular fluid (GCF) in patients with EC and chronic periodontitis (CP) to address this gap. Materials and methods: In a ...
متن کاملInterrelationship between diabetes and periodontitis: a review.
Evidence for the link between periodontal disease and several systemic diseases is growing rapidly. Diabetes mellitus is a systemic disease with several major complications affecting both the quality and length of life causing morbidity and mortality. Periodontitis, one of these complications, is a chronic infection associated with substantial morbidity in the form of tooth loss and that affect...
متن کاملPeriodontal Infections and Atherosclerosis: Mechanisms of Association
The bacteria associated with periodontal infection as well the by-products of host-bacterial interactions can have potential systemic effects. The field of periodontal medicine has emerged on the basis of the above and explores the interaction between periodontitis and various systemic conditions, such as cardiovascular disease (CVD), diabetes and pregnancy-related complications. Atherosclerosi...
متن کاملEosinophilic Cellulitis: Report of a case and literature review
Eosinophilic cellulitis is a rare skin disorder may be idiopathic or be associated with other conditions. We present a 42- year- old female patient with bilateral atypical cellulitis – like lesions on her arms. The patient had a documented infection with Leptospira recently, and had a positive history for fascioliasis two years before.Histopathology examination of the l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2017